Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries
نویسندگان
چکیده
Abstract Reported incidence of pertussis in the European Union (EU) and Economic Area (EEA) varies may not reflect real situation, while vaccine-induced protection against diphtheria tetanus seems sufficient. We aimed to determine seroprevalence DTP antibodies EU/EEA countries within age groups 40–49 50–59 years. Eighteen collected around 500 samples between 2015 2018 (N = 10,302) which were analysed for IgG-DTP specific antibodies. The proportion sera with toxin antibody levels ?100 IU/mL, indicative recent exposure was comparable 13/18 countries, ranging 2.7–5.8%. For lacking protective level (<0.1 IU/mL) varied 22.8–82.0%. Here, we report that these indicates circulation B. across lack seroprotection is concern deserves further attention.
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ژورنال
عنوان ژورنال: Nature Communications
سال: 2021
ISSN: ['2041-1723']
DOI: https://doi.org/10.1038/s41467-021-23114-y